Butoxamine hydrochloride

Product Name
Butoxamine hydrochloride
CAS No.
5696-15-1
Chemical Name
Butoxamine hydrochloride
Synonyms
BW-64-9;NSC-106565;AIDS-156055;BUTOXAMINE HCL;Butaxamine USP/EP/BP;Butaxamine hydrochloride;BUTOXAMINE HYDROCHLORIDE;Butoxamine hydrochloride USP/EP/BP;α-(1-[t-butylamino]ethyl)-2,5-dimethoxybenzyl alcohol;ALPHA-[1-(T-BUTYLAMINO)ETHYL]-2,5-DIMETHOXYBENZYL ALCOHOL HYDROCHLORIDE
CBNumber
CB0392437
Molecular Formula
C15H26ClNO3
Formula Weight
303.82
MOL File
5696-15-1.mol
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B1385
Product name
Butoxamine hydrochloride
Purity
analytical standard, for drug analysis, mixture of diastereomers
Packaging
50mg
Price
$186
Updated
2024/03/01
Sigma-Aldrich
Product number
B1385
Product name
Butoxamine hydrochloride
Purity
analytical standard, for drug analysis, mixture of diastereomers
Packaging
500mg
Price
$876
Updated
2022/05/15
TRC
Product number
B809510
Product name
Butoxamine hydrochloride
Packaging
25mg
Price
$225
Updated
2021/12/16
TRC
Product number
B809510
Product name
Butoxamine hydrochloride
Packaging
50mg
Price
$445
Updated
2021/12/16
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Butoxamine hydrochloride Chemical Properties,Usage,Production

Originator

Butoxamine,SigmaAldrich

Uses

Antidiabetic; antihyperlipoproteinemic.

Uses

Butoxamine Hydrochloride is a beta-2 selective beta blocker. β2-adrenergic receptor(AR) antagonist; Antiarrhythmic;

Manufacturing Process

548.0 g (2 mol) of 2,5-dimethoxy-α-bromopropiophenone was dissolved in 500 ml of acetanitrile and 365.0 g (5 mol) of t-butylamine was added. The solution was allowed to stand at room temperature for 64 h and was then diluted with 2 L of anhydrous ether. The precipitated t-butylamine hydrobromide was filtered off and washed with ether. The filtrate and washings were concentrated in vacuo using a water-bath kept at 40°C. When most of the solvent had been removed, the residual material was dissolve in cold methanol and acidified with hydrochloric acid. The solution was then taken down to dryness in vacuo on the steam bath and the 1-(2,5- dimethoxyphenyl)-2-(t-butylamino)propiophenone was obtained, melting point 175-176°C (recrystallised from an ethanol ether mixture).
The bulk of the 1-(2,5-dimethoxyphenyl)-2-(t-butylamino)propiophenone was dissolved in methanol and hydrogenated over platinum (Adams' catalyst). After removal of the catalyst, the solvent was removed in vacuo and the residual solid was dissolved in water and the solution was washed with ether.
The aqueous layer was basified (dilute sodium hydroxide solution) and the base was taken into ether. After drying over anhydrous potassium carbonate, the ether was evaporated and the base was distille at 0.3 mm pressure. So the DL-erythro 1-(2,5-dimethoxyphenyl)-2-(t-butylamino)propanol, boiling point 127-128°C was obtained.

Therapeutic Function

Oral hypoglycemic, Antihyperlipidemic

Butoxamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Butoxamine hydrochloride Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58

5696-15-1, Butoxamine hydrochlorideRelated Search:


  • alpha-[1-(tert-butylamino)ethyl]-2,5-dimethoxybenzyl alcohol hydrochloride
  • BUTOXAMINE HYDROCHLORIDE
  • ALPHA-[1-(T-BUTYLAMINO)ETHYL]-2,5-DIMETHOXYBENZYL ALCOHOL HYDROCHLORIDE
  • α-(1-[t-butylamino]ethyl)-2,5-dimethoxybenzyl alcohol
  • AIDS-156055
  • Butaxamine hydrochloride
  • BW-64-9
  • NSC-106565
  • BUTOXAMINE HCL
  • Butoxamine hydrochloride USP/EP/BP
  • Butaxamine USP/EP/BP
  • 5696-15-1
  • C15H26ClNO3
  • Analytical Standards
  • Alphabetic
  • Analytical Chromatography Product Catalog
  • BI - BZ